{"product_id":"otx2-monoclonal-antibody-bt-mca0962","title":"OTX2 Monoclonal Antibody - BT-MCA0962","description":"\u003cp\u003eOTX2 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA0962-50, BT-MCA0962-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the bicoid subfamily of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and plays a role in brain, craniofacial, and sensory organ development. The encoded protein also influences the proliferation and differentiation of dopaminergic neuronal progenitor cells during mitosis. Mutations in this gene cause syndromic microphthalmia 5 (MCOPS5) and combined pituitary hormone deficiency 6 (CPHD6). This gene is also suspected of having an oncogenic role in medulloblastoma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Pseudogenes of this gene are known to exist on chromosomes two and nine.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and nuclear signaling; Developmental biology; Stem cells; Neuroscience\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: OTX2\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, IF, ICC, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Homeobox protein OTX2\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P32243; Mouse: P80206\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: OTX2; Homeobox protein OTX2; Orthodenticle homolog 2\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 5015\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238738452659,"sku":"BT-MCA0962-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238738485427,"sku":"BT-MCA0962-100","price":420.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_fd02cf51-493c-4672-80c6-2020cb92abb3.png?v=1769384262","url":"https:\/\/afsbio.com\/products\/otx2-monoclonal-antibody-bt-mca0962","provider":"AFSBio Inc.","version":"1.0","type":"link"}