{"product_id":"p130-cas-phospho-tyr165-rabbit-pab-es8061","title":"p130 Cas (phospho Tyr165) rabbit pAb - ES8061","description":"\u003cp\u003ep130 Cas (phospho Tyr165) rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES8061-50, ES8061-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: BCAR1, or CAS, is an Src (MIM 190090) family kinase substrate involved in various cellular events, including migration, survival, transformation, and invasion (Sawada et al., 2006 [PubMed 17129785]).[supplied by OMIM, May 2009],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: BCAR1; CAS; CASS1; CRKAS; Breast cancer anti-estrogen resistance protein 1; CRK-associated substrate; Cas scaffolding protein family member 1; p130cas\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC; IF; ELISA\u003c\/p\u003e\n\n\u003cp\u003eDilution: Western Blot: 1\/500 - 1\/2000. Immunohistochemistry: 1\/100 - 1\/300. ELISA: 1\/5000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human p130 Cas around the phosphorylation site of Tyr165. AA range:131-180\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 130kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 9564\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: P56945\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Cell junction, focal adhesion. Cytoplasm. Cell projection, axon. Unphosphorylated form localizes in the cytoplasm (By similarity). Localizes to focal adhesion sites following integrin engagement (By similarity).\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202370527411,"sku":"ES8061-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202370560179,"sku":"ES8061-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_e28ae5ee-cebd-42ff-a2c6-5213b5459911.png?v=1767127694","url":"https:\/\/afsbio.com\/products\/p130-cas-phospho-tyr165-rabbit-pab-es8061","provider":"AFSBio Inc.","version":"1.0","type":"link"}