{"product_id":"p19arf-rabbit-pab-a24462","title":"p19ARF Rabbit pAb - A24462","description":"p19ARF Rabbit pAb\n\nSizes: 20μL, 100μL\n\nCatalogue Numbers: A24462-20, A24462-100\n\nCitations, Manuals and MSDS Available upon request.\n\nBackground: Enables MDM2\/MDM4 family protein binding activity; enzyme inhibitor activity; and protein N-terminus binding activity. Involved in several processes, including negative regulation of lymphocyte proliferation; positive regulation of apoptotic process; and regulation of transcription, DNA-templated. Acts upstream of or within several processes, including negative regulation of cellular protein metabolic process; negative regulation of mammary gland epithelial cell proliferation; and positive regulation of apoptotic process involved in mammary gland involution. Located in cytoplasm and granular component. Part of protein-containing complex. Is expressed in several structures, including bone marrow; central nervous system; dorsal root ganglion; eye; and testis. Human ortholog (s) of this gene implicated in several diseases, including breast cancer (multiple) ; carcinoma (multiple) ; hematologic cancer (multiple) ; melanoma (multiple) ; and nervous system cancer (multiple). Orthologous to human CDKN2A (cyclin dependent kinase inhibitor 2A).\n\nCategory: Polyclonal Antibodies\n\nApplications: WB, ELISA\n\nCross-reactivity: Human\n\nProtein Weight: 19kDa\n\nObserved Molecular Weight: 17kDa\n\nImmunogen: Synthetic peptide\n\nSpecies: Mouse\n\nGeneID: 12578\n\nSWISS: Q64364\n\nAlternate Names: Arf; MTS1; Pctr1; p19ARF; p19\u003carf\u003e; ARF-INK4a; INK4a-ARF; Ink4a\/Arf; \n\nSource: Rabbit\n\nIsotype: IgG\n\nPurity: Affinity purification\n\nStorage: Store at -20℃. Avoid freeze \/ thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis),  pH 7.3.\n\nRecommended Dilutions: WB, 1:500 - 1:1000 ELISA, Recommended starting concentration is 1 μg\/mL. Please optimize the concentration based on your specific assay requirements.\n\nNCBI Alias: CDKN2A\n\nResearch Use Only\u003c\/arf\u003e","brand":"ABclonal","offers":[{"title":"20uL","offer_id":45189408030899,"sku":"A24462-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"100uL","offer_id":45189408063667,"sku":"A24462-100","price":417.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_e4f99e66-a216-4100-a171-3c1065567357.png?v=1766426507","url":"https:\/\/afsbio.com\/products\/p19arf-rabbit-pab-a24462","provider":"AFSBio Inc.","version":"1.0","type":"link"}