{"product_id":"p21-polyclonal-antibody-bz16989","title":"p21 Polyclonal Antibody-BZ16989","description":"\u003cp\u003ep21 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eProduct: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BZ16989-50, BZ16989-100\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P38936\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003ep21 Polyclonal Antibody-BZ16989\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-P, FC, IP,\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB: 1\/500-1\/1000 IHC: 1\/50-1\/100 IP: 1\/20 FC: 1\/50-1\/100\u003c\/p\u003e\n\n\u003cp\u003eBackground: The tumor suppressor protein p21 Waf1\/Cip1 acts as an inhibitor of cell cycle progression. It functions in stoichiometric relationships forming heterotrimeric complexes with cyclins and cyclin-dependent kinases. In association with CDK2 complexes, it serves to inhibit kinase activity and block progression through G1\/S. However, p21 may also enhance assembly and activity in complexes of CDK4 or CDK6 and cyclin D.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: Affinity Purified\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: IgG\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: Calculated MW: 18 kDa; Observed MW: 21 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of p21 Waf1\/Cip1 in MCF-7Lysates using p21 antibody., Immunohistochemistry analysis of paraffin-embedded Human Cholangiocarcinoma using p21 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: CDKN1A; CAP20; CDKN1; CIP1; MDA6; PIC1; SDI1; WAF1; Cyclin-dependent kinase inhibitor 1; CDK-interacting protein 1; Melanoma differentiation-associated protein 6; MDA-6; p21\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: A synthetic peptide of human p21\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42957332644019,"sku":"BZ16989-50","price":342.59,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42957332676787,"sku":"BZ16989-100","price":589.65,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_0aedca7c-869a-4902-ad47-c5c011693f3b.jpg?v=1705144966","url":"https:\/\/afsbio.com\/products\/p21-polyclonal-antibody-bz16989","provider":"AFSBio Inc.","version":"1.0","type":"link"}