{"product_id":"p2rx7-polyclonal-antibody-e-ab-63428","title":"P2RX7 Polyclonal Antibody - E-AB-63428","description":"\u003cp\u003eP2RX7 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-63428-60, E-AB-63428-120, E-AB-63428-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: P2RX7\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: P2RX7; P2X7\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Neuroscience\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: Q99572\u003c\/p\u003e\n\n\u003cp\u003eBackground: The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants have been identified, most of which fit nonsense-mediated decay (NMD) criteria.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human P2RX7\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:1000-1:2000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 14kDa\/31kDa\/35kDa\/41kDa\/49kDa\/58kDa\/68kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 75KDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146288070835,"sku":"E-AB-63428-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146288103603,"sku":"E-AB-63428-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146288136371,"sku":"E-AB-63428-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_41525bf0-1c7d-4836-a337-244c4301aab5.png?v=1710293051","url":"https:\/\/afsbio.com\/products\/p2rx7-polyclonal-antibody-e-ab-63428","provider":"AFSBio Inc.","version":"1.0","type":"link"}