{"product_id":"p2ry2-polyclonal-antibody-bs7856","title":"P2RY2 Polyclonal Antibody-BS7856","description":"\u003cp\u003eP2RY2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS7856-50, BS7856-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P41231\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB IF\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB: 1:500~1:2000\u003cbr\u003e\nIF: 1:50~1:200\u003c\/p\u003e\n\n\u003cp\u003eBackground: Nucleotides are emerging as important extracellular signaling molecules that mediate several effects, such as proliferation, differentiation, chemotaxis and cytokine release. The P2 receptor family is activated by the binding of nucleotides and is divided into two subfamilies, P2X and P2Y. The P2X receptor family is comprised of ligand-gated ion channels that allow for the increased permeability of calcium into the cell in response to extracellular ATP. The P2Y receptor family are G protein-coupled receptors which mediate the effects of extracellular nucleotides, primarily through the activation of phospholipase C. To some extent, the P2Y receptors can also activate potassium channels or, alternatively, inhibit adenylate cyclase and N-type calcium channels in response to extracellular nucleotides. The P2Y receptors are differentially expressed in several tissue types, such as heart, lung and brain. However, all P2Y receptors are expressed in leukocytes, which suggests a role for the P2Y receptor family in the activation of leukocytes and platelets in response to inflammation or vascular damage.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: P2RY2 polyclonal antibody detects endogenous levels of P2RY2 protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 50 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western Blot (WB) analysis of P2RY2 polyclonal antibody\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: ATP receptor; \u003cbr\u003e\nHP2U; \u003cbr\u003e\nHuman P2U nucleotide receptor mRNA complete cds; \u003cbr\u003e\nMGC20088; \u003cbr\u003e\nMGC40010; \u003cbr\u003e\nP2RU1; \u003cbr\u003e\nP2RY2; \u003cbr\u003e\nP2RY2_HUMAN; \u003cbr\u003e\nP2U; \u003cbr\u003e\nP2U nucleotide receptor; \u003cbr\u003e\nP2U purinoceptor 1; \u003cbr\u003e\nP2U receptor 1; \u003cbr\u003e\nP2U1; \u003cbr\u003e\nP2UR; \u003cbr\u003e\nP2Y purinoceptor 2; \u003cbr\u003e\nP2Y2; \u003cbr\u003e\nP2Y2R; \u003cbr\u003e\nPurinergic receptor; \u003cbr\u003e\nPurinergic receptor P2Y G protein coupled 2; \u003cbr\u003e\nPurinergic receptor P2Y2; \u003cbr\u003e\nPurinoceptor P2Y2;\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: Recombinant full length Human P2RY2.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42923475271859,"sku":"BS7856-50","price":342.59,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42923475304627,"sku":"BS7856-100","price":589.65,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_a92dfc6f-64a7-4a8d-bd7b-1e87f0172067.jpg?v=1703850171","url":"https:\/\/afsbio.com\/products\/p2ry2-polyclonal-antibody-bs7856","provider":"AFSBio Inc.","version":"1.0","type":"link"}