{"product_id":"p300-acetyl-lys1558-acetyl-lys1560-polyclonal-antibody-ra28333","title":"p300 (Acetyl Lys1558\/Acetyl Lys1560) Polyclonal Antibody - RA28333","description":"\u003cp\u003ep300 (Acetyl Lys1558\/Acetyl Lys1560) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA28333-50, RA28333-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: E1A binding protein p300 (EP300) Homo sapiens This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer. [provided by RefSeq, Jul 2008],\u003c\/p\u003e\n\n\u003cp\u003eCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eStorage Instructions: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eRecommended dilutions: Western Blot: 1\/500 - 1\/2000. ELISA: 1\/10000. Not yet tested in other applications.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Names: EP300; P300; Histone acetyltransferase p300; p300 HAT; E1A-associated protein p300\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; ELISA\u003c\/p\u003e\n\n\u003cp\u003eSpecies Cross-Reactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eGeneID (Human): 2033\u003c\/p\u003e\n\n\u003cp\u003eProtein MW (KDa): 300\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q09472\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45121449197747,"sku":"RA28333-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45121449230515,"sku":"RA28333-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_78dc58fe-684b-422f-98ec-7849caf6a1c7.png?v=1773347789","url":"https:\/\/afsbio.com\/products\/p300-acetyl-lys1558-acetyl-lys1560-polyclonal-antibody-ra28333","provider":"AFSBio Inc.","version":"1.0","type":"link"}