{"product_id":"p3h2-polyclonal-antibody-bt-ap12646","title":"P3H2 Polyclonal Antibody - BT-AP12646","description":"\u003cp\u003eP3H2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP12646-20, BT-AP12646-50, BT-AP12646-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the prolyl 3-hydroxylase subfamily of 2-oxo-glutarate-dependent dioxygenases. These enzymes play a critical role in collagen chain assembly, stability and cross-linking by catalyzing post-translational 3-hydroxylation of proline residues. Mutations in this gene are associated with nonsyndromic severe myopia with cataract and vitreoretinal degeneration, and downregulation of this gene may play a role in breast cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Neuroscience; Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: LEPREL1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Prolyl 3-hydroxylase 2\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q8IVL5; Mouse: Q8CG71; Rat: Q4KLM6\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Prolyl 3-hydroxylase 2;EC 1.14.11.7;Leprecan-like protein 1;Myxoid liposarcoma-associated protein 4\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 55214\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239274635443,"sku":"BT-AP12646-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239274668211,"sku":"BT-AP12646-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239274700979,"sku":"BT-AP12646-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_16ba8fff-687c-4b10-a66a-513275e4466e.png?v=1769392375","url":"https:\/\/afsbio.com\/products\/p3h2-polyclonal-antibody-bt-ap12646","provider":"AFSBio Inc.","version":"1.0","type":"link"}