{"product_id":"p44-42-mapk-erk1-2-monoclonal-antibody-6c10-bt-mca0974","title":"P44\/42 MAPK (ERK1\/2) Monoclonal Antibody (6C10) - BT-MCA0974","description":"\u003cp\u003eP44\/42 MAPK (ERK1\/2) Monoclonal Antibody (6C10)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-MCA0974-20, BT-MCA0974-50, BT-MCA0974-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal transduction; Stem cells; Neuroscience\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: MAPK3\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, IF\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human,Rat,Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P27361; P28482\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: MAPK3; ERK1; PRKM3; Mitogen-activated protein kinase 3; MAP kinase 3; MAPK 3; ERT2; Extracellular signal-regulated kinase 1; ERK-1; Insulin-stimulated MAP2 kinase; MAP kinase isoform p44; p44-MAPK; Microtubule-associated protein 2 kinase; p\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 5594(5595)\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240045076659,"sku":"BT-MCA0974-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240045109427,"sku":"BT-MCA0974-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240045142195,"sku":"BT-MCA0974-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_414cc6b7-6605-459c-8f19-15408776b76a.png?v=1769402620","url":"https:\/\/afsbio.com\/products\/p44-42-mapk-erk1-2-monoclonal-antibody-6c10-bt-mca0974","provider":"AFSBio Inc.","version":"1.0","type":"link"}