{"product_id":"p44-42-mapk-erk1-2-mouse-mab-em1221","title":"P44\/42 MAPK (ERK1\/2) Mouse mAb - EM1221","description":"\u003cp\u003eP44\/42 MAPK (ERK1\/2) Mouse mAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: EM1221-50, EM1221-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Mitogen-activated protein kinases (MAPKs) are a widely conserved family of serine\/threonine protein kinases involved in many cellular programs such as cell proliferation, differentiation, motility, and death. The p44\/42 MAPK (Erk1\/2) signaling pathway can be activated in response to a diverse range of extracellular stimuli including mitogens, growth factors, and cytokines and is an important target in the diagnosis and treatment of cancer.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Name: MAPK, Mitogen-activated protein Kinase, PRKM2, MK01\u003c\/p\u003e\n\n\u003cp\u003eSource: Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:1, 000-2, 000  IHC  1:100-200\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic Peptide\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG1\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 44, 42kDa\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 5594\/5595\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: P27361\/P28482\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Nucleus\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45201992253619,"sku":"EM1221-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45201992286387,"sku":"EM1221-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_27d38402-2c08-4978-af13-b247f9d37ac6.png?v=1767119507","url":"https:\/\/afsbio.com\/products\/p44-42-mapk-erk1-2-mouse-mab-em1221","provider":"AFSBio Inc.","version":"1.0","type":"link"}