{"product_id":"p4hb-monoclonal-antibody-bt-mca2373","title":"P4HB Monoclonal Antibody - BT-MCA2373","description":"\u003cp\u003eP4HB Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA2373-50, BT-MCA2373-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes the beta subunit of prolyl 4-hydroxylase, a highly abundant multifunctional enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds. Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Others\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: P4HB\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC, ICC, FCM\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 4E10C6F6\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG2a\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: P4HB\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human P4HB (AA:309-508) expressed in mammalian.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Purified antibody in PBS with 0.05% sodium azide\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 57.1kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: P07237\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: DSI,GIT, PDI,PHDB, PDIA1,PO4DB, PO4HB,PROHB,CLCRP1, ERBA2L,P4Hbeta\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 5034\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238520512691,"sku":"BT-MCA2373-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238520545459,"sku":"BT-MCA2373-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_8b340d9f-c9f3-4a1c-b6c1-c8ba7f0de613.png?v=1769382102","url":"https:\/\/afsbio.com\/products\/p4hb-monoclonal-antibody-bt-mca2373","provider":"AFSBio Inc.","version":"1.0","type":"link"}