{"product_id":"p4hb-polyclonal-antibody-bs6048","title":"P4HB Polyclonal Antibody-BS6048","description":"\u003cp\u003eP4HB Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS6048-50, BS6048-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P07237\u003c\/p\u003e \n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC, IF\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB\t1:500 - 1:2000  IHC\t1:50 - 1:200  IF\t1:50 - 1:200\u003c\/p\u003e\n\n\u003cp\u003eBackground: Oxidoreductase-protein disulfide isomerase (PDI) is a homodimer consisting of subunits that catalyzes thiol-disulfide exchange, mediates folding of newly synthesized proteins and functions as a molecular chaperone. PDI localizes to the lumen of the endoplasmic reticulum (ER), where in conjunction with folding-helper proteins, such as immunoglobulin heavy chain binding protein (BiP), mediates tertiary and quaternary protein-processing. Cell surface PDI induces sulfhydryl-mediated conformational changes in integrin-mediated adhesion receptor-ligand interactions, thereby regulating integrin responses and cell adhesion. Additionally, PDI functions as a subunit of two more complex enzyme systems: the prolyl-4-hydroxylase and the triacylglycerol transfer proteins.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: P4HB polyclonal antibody detects endogenous levels of P4HB protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 57 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: WesternBlot (WB) analysis of P4HB polyclonal antibody, Immunofluorescence analysis of Hela cells, using P4HB polyclonal antibody\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: Cellular thyroid hormone binding protein; \u003cbr\u003e\nCellular thyroid hormone-binding protein; \u003cbr\u003e\nCollagen prolyl 4 hydroxylase beta; \u003cbr\u003e\nDisulphide Isomerase; \u003cbr\u003e\nDSI; \u003cbr\u003e\nEC 5.3.4.1; \u003cbr\u003e\nEndoplasmic reticulum resident protein 59; \u003cbr\u003e\nER protein 59; \u003cbr\u003e\nERBA2L; \u003cbr\u003e\nERp59; \u003cbr\u003e\nGIT; \u003cbr\u003e\nGltathione insulin transhydrogenase; \u003cbr\u003e\nGlutathione insulin transhydrogenase; \u003cbr\u003e\nP4HB; \u003cbr\u003e\nP4Hbeta; \u003cbr\u003e\np55; \u003cbr\u003e\nPDI; \u003cbr\u003e\nPDIA1; \u003cbr\u003e\nPDIA1; \u003cbr\u003e\nPDIR; \u003cbr\u003e\nPHDB; \u003cbr\u003e\nPO4DB; \u003cbr\u003e\nPO4HB; \u003cbr\u003e\nProcollagen proline 2 oxoglutarate 4 dioxygenase (proline 4 hydroxylase) beta polypeptide (pro\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant full length Human P4HB.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42989563707571,"sku":"BS6048-50","price":342.59,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42989563740339,"sku":"BS6048-100","price":589.65,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_5b0d5d7c-c6e8-4d8c-8be9-643c411b562b.jpg?v=1706095396","url":"https:\/\/afsbio.com\/products\/p4hb-polyclonal-antibody-bs6048","provider":"AFSBio Inc.","version":"1.0","type":"link"}