{"product_id":"p57-kip2-monoclonal-antibody-mb12177","title":"p57 Kip2 Monoclonal Antibody-MB12177","description":"\u003cp\u003ep57 Kip2 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: MB12177-50, MB12177-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P49918\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-P, IP,\u003c\/p\u003e \n\n\u003cp\u003eAll Applications: WB: 1\/500-1\/1000  IHC: 1\/50-1\/100  IP: 1\/20\u003c\/p\u003e  \n\n\u003cp\u003eBackground: p27 Kip1 is a member of the Cip\/Kip family of cyclin-dependent kinase inhibitors. Like its relatives, p57 Kip2 and p21 Waf1\/Cip1, the ability to enforce the G1 restriction point is derived from its inhibitory binding to CDK2\/cyclin E and other CDK\/cyclin complexes. Expression levels of p27 are upregulated in quiescent cells and in cells treated with cAMP or other negative cell cycle regulators.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: Affinity Purified\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: IgG\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: Calculated MW: 32 kDa; Observed MW: 57 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of p57 Kip2 in A549, U2OS lysates using p57 Kip2 antibody., Immunohistochemistry analysis of paraffin-embedded Human breast cancer using p57 Kip2 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: CDKN1C; KIP2; Cyclin-dependent kinase inhibitor 1C; Cyclin-dependent kinase inhibitor p57; p57Kip2\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: A synthetic peptide of human p57 Kip2\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42975409930419,"sku":"MB12177-50","price":424.94,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42975409963187,"sku":"MB12177-100","price":655.54,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_8c30645e-dd84-4b42-88b3-50fb768f2942.jpg?v=1705665607","url":"https:\/\/afsbio.com\/products\/p57-kip2-monoclonal-antibody-mb12177","provider":"AFSBio Inc.","version":"1.0","type":"link"}