{"product_id":"p63-α-3f11-mouse-mab-em1404","title":"P63-α (3F11) Mouse mAb - EM1404","description":"\u003cp\u003eP63-α (3F11) Mouse mAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: EM1404-50, EM1404-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: p63 can induce p53-responsive genes and apoptosis, mutation of p63 rarely results in tumors . Research investigators frequently observe amplification of the p63 gene in squamous cell carcinomas of the lung, head and neck . The p63 gene contains an alternative transcription initiation site that yields a 40 kDa δNp63 lacking the transactivation domain, and alternative splicing at the carboxy-terminus yields the α, β, and γ isoforms .\u003c\/p\u003e\n\n\u003cp\u003eSource: Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:1, 000-2, 000   IHC:1; 100-1:200\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic Peptide\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG1\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 50-80kDa\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 8626\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: Q9H3D4\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Nucleus\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45201670537395,"sku":"EM1404-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45201670570163,"sku":"EM1404-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_a7921bc2-6692-49b2-936f-e36f6fa97830.png?v=1767109000","url":"https:\/\/afsbio.com\/products\/p63-%ce%b1-3f11-mouse-mab-em1404","provider":"AFSBio Inc.","version":"1.0","type":"link"}