{"product_id":"p63-phospho-ser160-162-rabbit-polyclonal-antibody-bt-ap11745","title":"p63 (Phospho-Ser160\/162) Rabbit Polyclonal Antibody - BT-AP11745","description":"\u003cp\u003ep63 (Phospho-Ser160\/162) Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP11745-20, BT-AP11745-50, BT-AP11745-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the p53 family of transcription factors. The functional domains of p53 family proteins include an N-terminal transactivation domain| a central DNA-binding domain and an oligomerization domain. Alternative splicing of this gene and the use of alternative promoters results in multiple transcript variants encoding different isoforms that vary in their functional properties. These isoforms function during skin development and maintenance| adult stem\/progenitor cell regulation| heart development and premature aging. Some isoforms have been found to protect the germline by eliminating oocytes or testicular germ cells that have suffered DNA damage. Mutations in this gene are associated with ectodermal dysplasia| and cleft lip\/palate syndrome 3 (EEC3); split-hand\/foot malformation 4 (SHFM4); ankyloblepharon-ectodermal defects-cleft lip\/palate; ADULT syndrome (acro-dermato-ungual-lacrim\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and nuclear signaling; Cell biology; Cancer\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: TP63\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: p63\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q9H3D4; Mouse: O88898; Rat: Q9JJP6\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: p63;Ser160\/162; Tumor protein 63; p63; Chronic ulcerative stomatitis protein; CUSP; Keratinocyte transcription factor KET; Transformation-related protein 63; TP63; Tumor protein p73-like; p73L; p40; p51\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 8626; Mouse: 22061; Rat: 246334\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239012982963,"sku":"BT-AP11745-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239013015731,"sku":"BT-AP11745-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239013048499,"sku":"BT-AP11745-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_d6765306-f5be-46fd-b7e8-fb3d952729ca.png?v=1769387921","url":"https:\/\/afsbio.com\/products\/p63-phospho-ser160-162-rabbit-polyclonal-antibody-bt-ap11745","provider":"AFSBio Inc.","version":"1.0","type":"link"}