{"product_id":"p70-s6-kinase-mouse-monoclonal-antibody-1c7-bt-mca0982","title":"P70 S6 Kinase mouse Monoclonal Antibody (1C7) - BT-MCA0982","description":"\u003cp\u003eP70 S6 Kinase mouse Monoclonal Antibody (1C7)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-MCA0982-20, BT-MCA0982-50, BT-MCA0982-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the ribosomal S6 kinase family of serine\/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and nuclear signaling; Cell biology; Signal transduction; Metabolism\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: RPS6KB1\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC-p, IF\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human,Rat,Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: RPS6KB1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P23443; Mouse: Q8BSK8; Rat: P67999\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: RPS6KB1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 6198\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45240045273267,"sku":"BT-MCA0982-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45240045306035,"sku":"BT-MCA0982-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45240045338803,"sku":"BT-MCA0982-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_1efdf67a-c25a-4906-8150-23ccc3624c84.png?v=1769402623","url":"https:\/\/afsbio.com\/products\/p70-s6-kinase-mouse-monoclonal-antibody-1c7-bt-mca0982","provider":"AFSBio Inc.","version":"1.0","type":"link"}