{"product_id":"p70-s6-kinasealpha-polyclonal-antibody-bt-ap06856","title":"p70 S6 kinaseAlpha Polyclonal Antibody - BT-AP06856","description":"\u003cp\u003ep70 S6 kinaseAlpha Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP06856-20, BT-AP06856-50, BT-AP06856-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: RPS6KB1 (ribosomal protein S6 kinase B1) encodes a member of the ribosomal S6 kinase family of serine\/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of RPS6KB1 has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for RPS6KB1 on chromosome 17.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cell Biology\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: RPS6KB1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: p70 S6 kinase alpha Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 59140\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P23443; Mouse: Q8BSK8; Rat: P67999\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: RPS6KB1; STK14A; Ribosomal protein S6 kinase beta-1; S6K-beta-1; S6K1; 70 kDa ribosomal protein S6 kinase 1; P70S6K1; p70-S6K 1; Ribosomal protein S6 kinase I; Serine\/threonine-protein kinase 14A; p70\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 6198; Mouse: 72508; Rat: 83840\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239808000179,"sku":"BT-AP06856-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239808032947,"sku":"BT-AP06856-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239808065715,"sku":"BT-AP06856-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_aa0599f9-dcd7-4acf-9e55-53f112feb4a6.png?v=1769399456","url":"https:\/\/afsbio.com\/products\/p70-s6-kinasealpha-polyclonal-antibody-bt-ap06856","provider":"AFSBio Inc.","version":"1.0","type":"link"}