{"product_id":"p90rsk-rsk1-rps6ka1-rabbit-pab-a15718","title":"p90Rsk\/RSK1\/RPS6KA1 Rabbit pAb - A15718","description":"\u003cp\u003ep90Rsk\/RSK1\/RPS6KA1 Rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: A15718-20, A15718-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine\/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Polyclonal Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-P, IF\/ICC, ELISA\u003c\/p\u003e\n\n\u003cp\u003eCross-reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eProtein Weight: 83kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved Molecular Weight: 90kDa\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 6195\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q15418\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: RSK; HU-1; RSK1; p90Rsk; MAPKAPK1; MAPKAPK1A; p90Rsk\/RSK1\/RPS6KA1\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20℃. Avoid freeze \/ thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilutions: WB, 1:500 - 1:2000 IHC-P, 1:100 - 1:200 IF\/ICC, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg\/mL. Please optimize the concentration based on your specific assay requirements.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics Nuclear Signaling, Translation Control, Regulation of eIF4 and p70 S6 Kinase, Protein phosphorylation, Signal Transduction, G protein signaling, G-Protein-Coupled Receptors Signaling to MAPK Erk, Kinase, Serine threonine kinases, mTOR Signaling Pathway, MAPK-Erk Signaling Pathway, Cell Biology Developmental Biology, Apoptosis, Mitochondrial Control of Apoptosis, Inhibition of Apoptosis, Cell Cycle, Cell Cycle Control-G2 M DNA Damage Checkpoint, Microtubules, Immunology Inflammation, NF-kB Signaling Pathway, Neuroscience.\u003c\/p\u003e\n\n\u003cp\u003eNCBI Alias: RPS6KA1\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"20uL","offer_id":45189646155955,"sku":"A15718-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"100uL","offer_id":45189646188723,"sku":"A15718-100","price":417.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_7e012700-f3a4-47d8-9a36-1a44b02ea5d3.png?v=1766431769","url":"https:\/\/afsbio.com\/products\/p90rsk-rsk1-rps6ka1-rabbit-pab-a15718","provider":"AFSBio Inc.","version":"1.0","type":"link"}