{"product_id":"pa21b-polyclonal-antibody-bt-ap12717","title":"PA21B Polyclonal Antibody - BT-AP12717","description":"\u003cp\u003ePA21B Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP12717-20, BT-AP12717-50, BT-AP12717-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a secreted member of the phospholipase A2 (PLA2) class of enzymes, which is produced by the pancreatic acinar cells. The encoded calcium-dependent enzyme catalyzes the hydrolysis of the sn-2 position of membrane glycerophospholipids to release arachidonic acid (AA) and lysophospholipids. AA is subsequently converted by downstream metabolic enzymes to several bioactive lipophilic compounds (eicosanoids), including prostaglandins (PGs) and leukotrienes (LTs). The enzyme may be involved in several physiological processes including cell contraction, cell proliferation and pathological response.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Signal transduction; Metabolism\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: PLA2G1B\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Phospholipase A2\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P04054; Mouse: Q9Z0Y2; Rat: P04055\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Phospholipase A2;EC 3.1.1.4;Group IB phospholipase A2;Phosphatidylcholine 2-acylhydrolase 1B\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 5319\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239275618483,"sku":"BT-AP12717-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239275651251,"sku":"BT-AP12717-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239275684019,"sku":"BT-AP12717-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_a5769de5-29e8-43b7-b791-829dad7d1d69.png?v=1769392387","url":"https:\/\/afsbio.com\/products\/pa21b-polyclonal-antibody-bt-ap12717","provider":"AFSBio Inc.","version":"1.0","type":"link"}