{"product_id":"paics-polyclonal-antibody-e-ab-61974","title":"PAICS Polyclonal Antibody - E-AB-61974","description":"\u003cp\u003ePAICS Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-61974-60, E-AB-61974-120, E-AB-61974-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: PAICS\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: PAICS; ADE2; ADE2H1; AIRC; PAIS\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and Nuclear Signaling,Metabolism,Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, IF\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: P22234\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. The gene is closely linked and divergently transcribed with a locus that encodes an enzyme in the same pathway, and transcription of the two genes is coordinately regulated. The human genome contains several pseudogenes of this gene. Multiple transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human PAICS\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000, IF 1:10-1:100\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 47kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 47kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146219946163,"sku":"E-AB-61974-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146219978931,"sku":"E-AB-61974-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146220011699,"sku":"E-AB-61974-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_07c49f17-8e39-4ad1-92a6-d6b5f90c20e2.png?v=1710291836","url":"https:\/\/afsbio.com\/products\/paics-polyclonal-antibody-e-ab-61974","provider":"AFSBio Inc.","version":"1.0","type":"link"}