{"product_id":"pak-gamma-monoclonal-antibody-bt-mca0984","title":"PAK Gamma Monoclonal Antibody - BT-MCA0984","description":"\u003cp\u003ePAK Gamma Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA0984-50, BT-MCA0984-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine\/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal transduction; Cancer; Cell biology; Microbiology\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: PAK2\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, IF, ICC, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human,Monkey\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Serine,threonine-protein kinase PAK 2\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q13177; Mouse: Q8CIN4\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: PAK2; Serine; threonine-protein kinase PAK 2; Gamma-PAK; PAK65; S6; H4 kinase; p21-activated kinase 2; PAK-2; p58\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 5062\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238741500083,"sku":"BT-MCA0984-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238741532851,"sku":"BT-MCA0984-100","price":420.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_d5e136f9-df1c-43e0-9fc6-51c1efc7b2fa.png?v=1769384285","url":"https:\/\/afsbio.com\/products\/pak-gamma-monoclonal-antibody-bt-mca0984","provider":"AFSBio Inc.","version":"1.0","type":"link"}