{"product_id":"pak1-2-phospho-ser199-204-rabbit-polyclonal-antibody-bt-ap11770","title":"PAK1\/2 (Phospho-Ser199\/204) Rabbit Polyclonal Antibody - BT-AP11770","description":"\u003cp\u003ePAK1\/2 (Phospho-Ser199\/204) Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP11770-20, BT-AP11770-50, BT-AP11770-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a family member of serine\/threonine p21-activating kinases| known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling| and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Signal transduction; Cell biology; Cancer\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: PAK1\/2\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q13153; Mouse: O88643; Rat: P35465\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: PAK1\/2;Ser199\/204; Serine\/threonine-protein kinase PAK 1; EC 2.7.11.1; Alpha-PAK; p21-activated kinase 1; PAK-1; p65-PAK\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 5058; Rat: 29431\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45238925754547,"sku":"BT-AP11770-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45238925787315,"sku":"BT-AP11770-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238925820083,"sku":"BT-AP11770-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_5d4bcd1e-1a81-4123-b08a-2e31d14efc46.png?v=1769386778","url":"https:\/\/afsbio.com\/products\/pak1-2-phospho-ser199-204-rabbit-polyclonal-antibody-bt-ap11770","provider":"AFSBio Inc.","version":"1.0","type":"link"}