{"product_id":"pak2-7h3-monoclonal-antibody-mb3149","title":"PAK2 (7H3) Monoclonal Antibody-MB3149","description":"\u003cp\u003ePAK2 (7H3) Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: MB3149-50, MB3149-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: Q13177\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Monkey\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-F, IHC-P, ICC\/IF\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB: 1\/500-1\/1000  IHC: 1\/50-1\/100  IF: 1\/50-1\/200\u003c\/p\u003e  \n\n\u003cp\u003eBackground: The activated kinase acts on a variety of targets. Phosphorylates ribosomal protein S6, histone H4 and myelin basic protein. Full length PAK 2 stimulates cell survival and cell growth. The process is, at least in part, mediated by phosphorylation and inhibition of pro-apoptotic BAD.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: Affinity Purified\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: IgG1\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: Calculated MW: 58 kDa; Observed MW: 61 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of PAK2 in Jurkat, MCF-7 and Hela lysates using PAK2 antibody., Immunofluorescence analysis of PAK2 in Hela using PAK2 antibody. Blue: DRAQ5 fluorescent DNA dye., Immunohistochemistry analysis of paraffin-embedded Human lung cancer and gastric cancer using PAK2 antibody with DAB staining.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: PAK2; Serine\/threonine-protein kinase PAK 2; Gamma-PAK; PAK65; S6\/H4 kinase; p21-activated kinase 2; PAK-2; p58\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of PAK2 expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42999926620339,"sku":"MB3149-50","price":424.94,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42999926653107,"sku":"MB3149-100","price":655.54,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_21e118b5-7bbf-408e-a867-a8850d8e7984.jpg?v=1706358177","url":"https:\/\/afsbio.com\/products\/pak2-7h3-monoclonal-antibody-mb3149","provider":"AFSBio Inc.","version":"1.0","type":"link"}