{"product_id":"pak2-monoclonal-antibody-bt-mca3569","title":"PAK2 Monoclonal Antibody - BT-MCA3569","description":"\u003cp\u003ePAK2 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA3569-50, BT-MCA3569-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: PAK2, also known as P21 (CDKN1A)-activated kinase 2. The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine\/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. PAK2 is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell. PAK2 has been shown to interact with SH3KBP1, CDC42 and Abl gene.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cell Biology\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: PAK2\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC, ICC\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Monkey\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 3B5\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: PAK2\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of PAK2 expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Ascitic fluid containing 0.03% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 61kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Q13177\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: PAK65, PAKgamma\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 5062\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238639755443,"sku":"BT-MCA3569-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238639788211,"sku":"BT-MCA3569-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_70d43f7d-07e7-4a77-81ee-6bfbe2541b24.png?v=1769383317","url":"https:\/\/afsbio.com\/products\/pak2-monoclonal-antibody-bt-mca3569","provider":"AFSBio Inc.","version":"1.0","type":"link"}