{"product_id":"pan-14-3-3-rabbit-pab-a23674","title":"pan 14-3-3 Rabbit pAb - A23674","description":"\u003cp\u003epan 14-3-3 Rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: A23674-20, A23674-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a cell cycle checkpoint protein. The encoded protein binds to translation and initiation factors and functions as a regulator of mitotic translation. In response to DNA damage this protein plays a role in preventing DNA errors during mitosis.This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Polyclonal Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eCross-reactivity: Human, Mouse, Rat, African green monkey\u003c\/p\u003e\n\n\u003cp\u003eProtein Weight: 27kDa\/28kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved Molecular Weight: 27-29kDa\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant protein (or fragment)\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 10971\/7529\/7532\/7531\/7534\/7533\/2810\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P27348\/P31946\/P61981\/P62258\/P63104\/Q04917\/P31947\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: YWHA; S1C5; HS1; 14-3-3; pan 14-3-3\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20℃. Avoid freeze \/ thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis),  pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilutions: WB, 1:500 - 1:1000 ELISA, Recommended starting concentration is 1 μg\/mL. Please optimize the concentration based on your specific assay requirements.\u003c\/p\u003e\n\n\u003cp\u003eNCBI Alias: pan 14-3-3\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"20uL","offer_id":45189407408307,"sku":"A23674-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"100uL","offer_id":45189407441075,"sku":"A23674-100","price":417.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_fc682d11-bdc4-4003-b9f2-5f925c620c63.png?v=1766426493","url":"https:\/\/afsbio.com\/products\/pan-14-3-3-rabbit-pab-a23674","provider":"AFSBio Inc.","version":"1.0","type":"link"}