{"product_id":"pank2-rabbit-pab-a18502","title":"PANK2 Rabbit pAb - A18502","description":"\u003cp\u003ePANK2 Rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: A18502-20, A18502-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a protein belonging to the pantothenate kinase family and is the only member of that family to be expressed in mitochondria. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by acyl CoA species. Mutations in this gene are associated with HARP syndrome and pantothenate kinase-associated neurodegeneration (PKAN), formerly Hallervorden-Spatz syndrome. Alternative splicing, involving the use of alternate first exons, results in multiple transcripts encoding different isoforms.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Polyclonal Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eCross-reactivity: Mouse\u003c\/p\u003e\n\n\u003cp\u003eProtein Weight: 63kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved Molecular Weight: 63kDa\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide .\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 80025\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q9BZ23\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: HSS; HARP; PKAN; NBIA1; C20orf48; PANK2\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20℃. Avoid freeze \/ thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg\/mL. Please optimize the concentration based on your specific assay requirements.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction, Endocrine Metabolism, Neuroscience, Neurodegenerative Diseases.\u003c\/p\u003e\n\n\u003cp\u003eNCBI Alias: PANK2\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"20uL","offer_id":45189772574899,"sku":"A18502-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"100uL","offer_id":45189772607667,"sku":"A18502-100","price":417.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_dfdf7fa2-5e3c-44d6-a9ae-eeb3f30ee192.png?v=1766435152","url":"https:\/\/afsbio.com\/products\/pank2-rabbit-pab-a18502","provider":"AFSBio Inc.","version":"1.0","type":"link"}