{"product_id":"papp1-polyclonal-antibody-bt-ap12770","title":"PAPP1 Polyclonal Antibody - BT-AP12770","description":"\u003cp\u003ePAPP1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP12770-20, BT-AP12770-50, BT-AP12770-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a secreted metalloproteinase which cleaves insulin-like growth factor binding proteins (IGFBPs). It is thought to be involved in local proliferative processes such as wound healing and bone remodeling. Low plasma level of this protein has been suggested as a biochemical marker for pregnancies with aneuploid fetuses.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Cardiovascular; Cell biology\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: PAPPA\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Pappalysin-1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q13219; Mouse: Q8R4K8\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Pappalysin-1;EC 3.4.24.79;Insulin-like growth factor-dependent IGF-binding protein 4 protease;IGF-dependent IGFBP-4 protease;IGFBP-4ase;Pregnancy-associated plasma protein A;PAPP-A\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 5069\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239277355187,"sku":"BT-AP12770-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239277387955,"sku":"BT-AP12770-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239277420723,"sku":"BT-AP12770-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_e335c891-60a7-4c42-93a2-c4cdfef59ca9.png?v=1769392411","url":"https:\/\/afsbio.com\/products\/papp1-polyclonal-antibody-bt-ap12770","provider":"AFSBio Inc.","version":"1.0","type":"link"}