{"product_id":"parafibromin-polyclonal-antibody-bt-ap12785","title":"Parafibromin Polyclonal Antibody - BT-AP12785","description":"\u003cp\u003eParafibromin Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP12785-20, BT-AP12785-50, BT-AP12785-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3andapos; mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Epigenetics and nuclear signaling\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: CDC73\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Parafibromin\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q6P1J9; Mouse: Q8JZM7\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Parafibromin; Parafibromin; Cell division cycle protein 73 homolog; Hyperparathyroidism 2 protein\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 79577; Mouse: 214498\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239278338227,"sku":"BT-AP12785-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239278370995,"sku":"BT-AP12785-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239278403763,"sku":"BT-AP12785-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_48461b41-59c7-4892-9d86-046c1909a1d5.png?v=1769392430","url":"https:\/\/afsbio.com\/products\/parafibromin-polyclonal-antibody-bt-ap12785","provider":"AFSBio Inc.","version":"1.0","type":"link"}