{"product_id":"parl-monoclonal-antibody-bt-mca0988","title":"PARL Monoclonal Antibody - BT-MCA0988","description":"\u003cp\u003ePARL Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA0988-50, BT-MCA0988-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the rhomboid family of intramembrane serine proteases that is localized to the inner mitochondrial membrane. The encoded protein regulates mitochondrial remodeling and apoptosis through regulated substrate proteolysis. Proteolytic processing of the encoded protein results in the release of a small peptide, P-beta, which may transit to the nucleus. Mutations in this gene may be associated with Parkinson's disease.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Metabolism; Neuroscience; Cell biology; Cancer\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: PARL\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Presenilins-associated rhomboid-like protein mitochondrial\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q9H300; Mouse: Q5XJY4\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: PARL; PSARL; Presenilins-associated rhomboid-like protein; mitochondrial; Mitochondrial intramembrane cleaving protease PARL\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 55486\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238741991603,"sku":"BT-MCA0988-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238742024371,"sku":"BT-MCA0988-100","price":420.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_1f98e53b-fcba-4ca5-aaed-69983bf36739.png?v=1769384287","url":"https:\/\/afsbio.com\/products\/parl-monoclonal-antibody-bt-mca0988","provider":"AFSBio Inc.","version":"1.0","type":"link"}