{"product_id":"parp11-polyclonal-antibody-e-ab-11474","title":"PARP11 Polyclonal Antibody - E-AB-11474","description":"\u003cp\u003ePARP11 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-11474-60, E-AB-11474-120, E-AB-11474-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: PARP11\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: 5330431N24Rik; AI851877; C12orf6; DKFZp779H0122; HIN1L; MIB006; OTTMUSP00000027219; Poly (ADP ribose) polymerase family member 11; RGD1561791\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and Nuclear Signaling\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplication: IHC, ELISA\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q9NR21\u003c\/p\u003e\n\n\u003cp\u003eBackground: Poly(ADP-ribosylation) is a method of DNA damage-dependent posttranslational modification that helps to rescue injured proliferating cells from cell death. The PARP (poly(ADP-ribose) polymerase) proteins comprise a superfamily of enzymes that functionally modify histones and other nuclear proteins, thereby preventing cell death. PARPs use NAD+ as a substrate to catalytically transfer ADP-ribose residues onto protein acceptors; a process that, when repeated multiple times, leads to the formation of poly(ADPribose) chains on the protein.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 0.4 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant protein of human PARP11\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: IHC 1:50-1:200\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"200μL","offer_id":43124084211891,"sku":"E-AB-11474-200","price":558.6,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43124084244659,"sku":"E-AB-11474-120","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"60μL","offer_id":43124084277427,"sku":"E-AB-11474-60","price":200.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_86dcf461-4a91-4c2d-aff7-9a6db93844b2.png?v=1709723661","url":"https:\/\/afsbio.com\/products\/parp11-polyclonal-antibody-e-ab-11474","provider":"AFSBio Inc.","version":"1.0","type":"link"}