{"product_id":"parvalbumin-α-polyclonal-antibody-bs60382","title":"Parvalbumin α Polyclonal Antibody-BS60382","description":"\u003cp\u003eParvalbumin α Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS60382-50, BS60382-100\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: Parvalbumin alpha; PVALB; Parvalbumin-α\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P20472\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e \n\n\u003cp\u003eAll Applications: WB: 1:500~1:1000\u003c\/p\u003e\n\n\u003cp\u003eBackground: Parvalbumin is a small, stable protein containing EF-hand type calcium binding sites. It is involved in calcium signaling. Typically, this protein is broken into three domains, domains AB, CD and EF, each individually containing a helix-loop-helix motif. The AB domain houses a two amino-acid deletion in the loop region, whereas domains CD and EF contain the N-terminal and C-terminal, respectively. Calcium binding proteins like parvalbumin play a role in many physiological processes, namely cell-cycle regulation, second messenger production, muscle contraction, organization of microtubules and vision. Parvalbumin expressing neurons have also been found to be in connection with various areas of clinical interest such as Alzheimer’s disease, nervous system disorders, age-related cognitive defects and some forms of cancer.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: Parvalbumin α polyclonal antibody detects endogenous levels of Parvalbumin α protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 15 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot (WB) analysis of Parvalbumin α polyclonal antibody at 1:500 dilution\u003cbr\u003e\nLane 1: Hela cell lysate\u003cbr\u003e\nLane 2: Mouse skeletal muscle tissue lysate\u003cbr\u003e\nLane 3: Rat skeletal muscle tissue lysate\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: A synthetic peptide corresponding to residues in Human Parvalbumin α.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42913593688243,"sku":"BS60382-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42913593721011,"sku":"BS60382-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_cc38a4b7-d782-4a7c-be95-04a6352ee8c8.jpg?v=1703266453","url":"https:\/\/afsbio.com\/products\/parvalbumin-%ce%b1-polyclonal-antibody-bs60382","provider":"AFSBio Inc.","version":"1.0","type":"link"}