{"product_id":"pax-6-monoclonal-antibody-bt-mca0992","title":"Pax-6 Monoclonal Antibody - BT-MCA0992","description":"\u003cp\u003ePax-6 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA0992-50, BT-MCA0992-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a homeobox and paired domain-containing protein that binds DNA and functions as a regulator of transcription. Activity of this protein is key in the development of neural tissues, particularly the eye. This gene is regulated by multiple enhancers located up to hundreds of kilobases distant from this locus. Mutations in this gene or in the enhancer regions can cause ocular disorders such as aniridia and Peter's anomaly. Use of alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and nuclear signaling; Developmental biology; Stem cells; Neuroscience\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: PAX6\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, FCM, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Paired box protein Pax-6\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P26367; Mouse: P63015\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: PAX6; AN2; Paired box protein Pax-6; Aniridia type II protein; Oculorhombin\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 5080\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238742450355,"sku":"BT-MCA0992-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238742483123,"sku":"BT-MCA0992-100","price":420.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_f5ab3a53-29a4-4e56-8112-80da88ca7996.png?v=1769384292","url":"https:\/\/afsbio.com\/products\/pax-6-monoclonal-antibody-bt-mca0992","provider":"AFSBio Inc.","version":"1.0","type":"link"}