{"product_id":"pax3-polyclonal-antibody-bt-ap12809","title":"PAX3 Polyclonal Antibody - BT-AP12809","description":"\u003cp\u003ePAX3 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP12809-20, BT-AP12809-50, BT-AP12809-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2;13)(q35;q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Developmental biology; Epigenetics and nuclear signaling; Stem cells\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: PAX3\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Paired box protein Pax-3\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P23760; Mouse: P24610\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Paired box protein Pax-3;HuP2\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 5077\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239279288499,"sku":"BT-AP12809-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239279321267,"sku":"BT-AP12809-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239279354035,"sku":"BT-AP12809-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_dccc7b64-d433-4ff7-976e-e670c23d3b69.png?v=1769392442","url":"https:\/\/afsbio.com\/products\/pax3-polyclonal-antibody-bt-ap12809","provider":"AFSBio Inc.","version":"1.0","type":"link"}