{"product_id":"pbef1-monoclonal-antibody-bt-mca4046","title":"PBEF1 Monoclonal Antibody - BT-MCA4046","description":"\u003cp\u003ePBEF1 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA4046-50, BT-MCA4046-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: PBEF1: nicotinamide phosphoribosyltransferase. This gene encodes a protein that catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein is an adipokine that is localized to the bloodstream and has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It also activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Others\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: PBEF1\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 1D3A12\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: PBEF1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of PBEF1 (aa338-479) expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Ascitic fluid containing 0.03% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: P43490\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: VF, PBEF, PBEF1, VISFATIN, NAMPT\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 10135\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238369026227,"sku":"BT-MCA4046-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238369058995,"sku":"BT-MCA4046-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_ca4748b8-2d13-4ef6-bacf-c0080ccfc44a.png?v=1769379285","url":"https:\/\/afsbio.com\/products\/pbef1-monoclonal-antibody-bt-mca4046","provider":"AFSBio Inc.","version":"1.0","type":"link"}