{"product_id":"pbxip1-polyclonal-antibody-e-ab-52665","title":"PBXIP1 Polyclonal Antibody - E-AB-52665","description":"\u003cp\u003ePBXIP1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-52665-60, E-AB-52665-120, E-AB-52665-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: PBXIP1\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: 4732463H20Rik; Hematopoietic PBX interacting protein ; HPIP ; MGC38361; Pre B cell leukemia homeobox interacting protein 1; RP11-307C12.2\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and Nuclear Signaling, Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplication: IHC, ELISA\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: Q96AQ6\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene interacts with the PBX1 homeodomain protein, inhibiting its transcriptional activation potential by preventing its binding to DNA. The encoded protein, which is primarily cytosolic but can shuttle to the nucleus, also can interact with estrogen receptors alpha and beta and promote the proliferation of breast cancer, brain tumors, and lung cancer. Several transcript variants encoding different isoforms have been found for this gene. More variants exist, but their full-length natures have yet to be determined.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 0.66 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Fusion protein of human PBXIP1\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Antigen affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: IHC 1:30-1:150, ELISA 1:5000-1:10000\u003c\/p\u003e\n\n \n\n \n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43133504520371,"sku":"E-AB-52665-60","price":200.2,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43133504553139,"sku":"E-AB-52665-120","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43133504585907,"sku":"E-AB-52665-200","price":558.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_39b61767-2623-44c5-aeff-80c8a480ba72.png?v=1709899585","url":"https:\/\/afsbio.com\/products\/pbxip1-polyclonal-antibody-e-ab-52665","provider":"AFSBio Inc.","version":"1.0","type":"link"}