{"product_id":"pbxip1-polyclonal-antibody-e-ab-63905","title":"PBXIP1 Polyclonal Antibody - E-AB-63905","description":"\u003cp\u003ePBXIP1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-63905-60, E-AB-63905-120, E-AB-63905-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: PBXIP1\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: PBXIP1; HPIP\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and Nuclear Signaling, Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: Q96AQ6\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene interacts with the PBX1 homeodomain protein, inhibiting its transcriptional activation potential by preventing its binding to DNA. The encoded protein, which is primarily cytosolic but can shuttle to the nucleus, also can interact with estrogen receptors alpha and beta and promote the proliferation of breast cancer, brain tumors, and lung cancer. Several transcript variants encoding different isoforms have been found for this gene. More variants exist, but their full-length natures have yet to be determined.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human PBXIP1 (NP_065385.2).\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB \t1:1000-1:2000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 72kDa\/77kDa\/80kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 110kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146304487603,"sku":"E-AB-63905-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146304520371,"sku":"E-AB-63905-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146304553139,"sku":"E-AB-63905-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_c12ec218-f8aa-4787-8c61-e77e29906dd1.png?v=1710293332","url":"https:\/\/afsbio.com\/products\/pbxip1-polyclonal-antibody-e-ab-63905","provider":"AFSBio Inc.","version":"1.0","type":"link"}