{"product_id":"pcaf-acetyl-lys428-polyclonal-antibody-bt-ap06966","title":"PCAF (Acetyl Lys428) Polyclonal Antibody - BT-AP06966","description":"\u003cp\u003ePCAF (Acetyl Lys428) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP06966-20, BT-AP06966-50, BT-AP06966-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and\/or differentiation, including c-jun and the adenoviral oncoprotein E1A. lysine acetyltransferase 2B associates with p300\/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300\/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that lysine acetyltransferase 2B plays a direct role in transcriptional regulation.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cell Biology\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: KAT2B\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: PCAF (Acetyl Lys428) Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 93013\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q92831; Mouse: Q9JHD1\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: KAT2B; PCAF; Histone acetyltransferase KAT2B; Histone acetyltransferase PCAF; Histone acetylase PCAF; Lysine acetyltransferase 2B; P300\/CBP-associated factor; P\/CAF\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 8850; Mouse: 18519\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239817470131,"sku":"BT-AP06966-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239817502899,"sku":"BT-AP06966-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239817535667,"sku":"BT-AP06966-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_b25d23b3-bf90-4fed-aeb4-4b3eda8dc206.png?v=1769399562","url":"https:\/\/afsbio.com\/products\/pcaf-acetyl-lys428-polyclonal-antibody-bt-ap06966","provider":"AFSBio Inc.","version":"1.0","type":"link"}