{"product_id":"pcb-polyclonal-antibody-ra21425","title":"PCB Polyclonal Antibody - RA21425","description":"PCB Polyclonal Antibody\n\nSizes: 50μL, 100μL\n\nCatalogue Numbers: RA21425-50, RA21425-100\n\nCitations, Manuals and MSDS Available upon request.\n\nBackground: pyruvate carboxylase (PC) Homo sapiens This gene encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008],\n\nCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\n\nStorage Instructions: -20°C\/1 year\n\nRecommended dilutions: Western Blot: 1\/500 - 1\/2000. IHC-p: 1:100-300 ELISA: 1\/20000. IF 1:100-300 Not yet tested in other applications.\n\nAlternative Names: PC; Pyruvate carboxylase; mitochondrial; Pyruvic carboxylase; PCB\n\nApplications: WB; IHC-p; IF\/ICC; ELISA\n\nSpecies Cross-Reactivity: Human; Mouse; Rat\n\nGeneID (Human): 5091\n\nProtein MW (KDa): 120\n\nSWISS: P11498\n\nSource: Rabbit\n\nResearch Use Only","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45121065550003,"sku":"RA21425-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45121065582771,"sku":"RA21425-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_7d49c1ca-20a6-4424-b834-987bdf89b760.png?v=1773370323","url":"https:\/\/afsbio.com\/products\/pcb-polyclonal-antibody-ra21425","provider":"AFSBio Inc.","version":"1.0","type":"link"}