{"product_id":"pcbp2-polyclonal-antibody-bt-ap12842","title":"PCBP2 Polyclonal Antibody - BT-AP12842","description":"\u003cp\u003ePCBP2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP12842-20, BT-AP12842-50, BT-AP12842-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene appears to be multifunctional. Along with PCBP-1 and hnRNPK, it is one of the major cellular poly(rC)-binding proteins. The encoded protein contains three K-homologous (KH) domains which may be involved in RNA binding. Together with PCBP-1, this protein also functions as a translational coactivator of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES, promoting poliovirus RNA replication by binding to its 5andapos;-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. This multiexon structural mRNA is thought to be retrotransposed to generate\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics and nuclear signaling; Microbiology\u003c\/p\u003e \n\n\u003cp\u003eTarget Protein: PCBP2\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Poly\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q15366; Mouse: Q61990\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Poly;rC-binding protein 2;Alpha-CP2;Heterogeneous nuclear ribonucleoprotein E2;hnRNP E2\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 5094\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239279812787,"sku":"BT-AP12842-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239279845555,"sku":"BT-AP12842-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239279878323,"sku":"BT-AP12842-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_2894e12a-0aa1-4127-a053-74ec1c5fde94.png?v=1769392449","url":"https:\/\/afsbio.com\/products\/pcbp2-polyclonal-antibody-bt-ap12842","provider":"AFSBio Inc.","version":"1.0","type":"link"}