{"product_id":"pcda8-rabbit-polyclonal-antibody-bt-ap11818","title":"PCDA8 Rabbit Polyclonal Antibody - BT-AP11818","description":"\u003cp\u003ePCDA8 Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP11818-20, BT-AP11818-50, BT-AP11818-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene is a member of the protocadherin alpha gene cluster| one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons| or variable exons| are followed by downstream C-terminal exons| or constant exons| which are shared by all genes in the cluster. The large| uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Neuroscience; Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: PCDHA8\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: PCDA8\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q9Y5H6\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: PCDA8; Protocadherin alpha-8; PCDH-alpha-8\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 56140\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239014064307,"sku":"BT-AP11818-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239014097075,"sku":"BT-AP11818-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239014129843,"sku":"BT-AP11818-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_036f99e2-1597-4cb5-8e97-c064e2e4c2c8.png?v=1769387936","url":"https:\/\/afsbio.com\/products\/pcda8-rabbit-polyclonal-antibody-bt-ap11818","provider":"AFSBio Inc.","version":"1.0","type":"link"}