{"product_id":"pcdhb4-polyclonal-antibody-bs77440","title":"PCDHB4 Polyclonal Antibody-BS77440","description":"PCDHB4 Polyclonal Antibody\n\nProduct: 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\n\nSizes: 50µl, 100µl\n\nCatalogue Numbers: BS77440-50, BS77440-100\n\nSwiss-Prot: Q9Y5E5\n\nHost: Rabbit\n\nPCDHB4 Polyclonal Antibody-BS77440\n\nStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\n\nReactivity: Human, Mouse, Rat\n\nApplications: WB, IF\/ICC\n\nAll Applications: WB,1:500 - 1:2000  |  IF\/ICC,1:50 - 1:200\n\nBackground: This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections. [provided by RefSeq, Jul 2008]\n\nPurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\n\nSpecificity: Unmodification\n\nBioworld Molecular Weight: 87kDa\n\nNote: For research use only, not for use in diagnostic procedure.\n\nExtra Notes: Western blot analysis of extracts of various cell lines, using PCDHB4 antibody at 1:1000 dilution.\nSecondary antibody: HRP Goat Anti-Rabbit IgG at 1:10000 dilution.\nLysates\/proteins: 25ug per lane.\nBlocking buffer: 3% non-fat dry milk in TBST.\nDetection: ECL Basic Kit.\nExposure time: 5s., Immunofluorescence analysis of L929 cells using PCDHB4 Rabbit pAb at dilution of 1:100. Blue: DAPI for nuclear staining.\n\nAlternative Name: PCDH-BETA4; PCDHB4\n\nImmunogen: Recombinant fusion protein of human PCDHB4(NP_061761.1).\n\nModification: Unmodified\n\nConjugate: Unconjugated","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42960064938163,"sku":"BS77440-50","price":342.59,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42960064970931,"sku":"BS77440-100","price":589.65,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_8c01d843-95c5-416b-aef7-f8bd98754667.jpg?v=1705231139","url":"https:\/\/afsbio.com\/products\/pcdhb4-polyclonal-antibody-bs77440","provider":"AFSBio Inc.","version":"1.0","type":"link"}