{"product_id":"pcna-polyclonal-antibody-bt-ap12847","title":"PCNA Polyclonal Antibody - BT-AP12847","description":"\u003cp\u003ePCNA Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP12847-20, BT-AP12847-50, BT-AP12847-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Cancer; Cell biology; Epigenetics and nuclear signaling; Tags and cell markers\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: PCNA\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: PCNA\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P12004; Mouse: P17918\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: PCNA; Proliferating cell nuclear antigen; PCNA; Cyclin\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 5111; Mouse: 18538\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239280468147,"sku":"BT-AP12847-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239280500915,"sku":"BT-AP12847-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239280533683,"sku":"BT-AP12847-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_80f71eba-5a55-4f4b-8035-a624d6804c61.png?v=1769392458","url":"https:\/\/afsbio.com\/products\/pcna-polyclonal-antibody-bt-ap12847","provider":"AFSBio Inc.","version":"1.0","type":"link"}