{"product_id":"pcnt-polyclonal-antibody-bt-ap12848","title":"PCNT Polyclonal Antibody - BT-AP12848","description":"\u003cp\u003ePCNT Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP12848-20, BT-AP12848-50, BT-AP12848-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene binds to calmodulin and is expressed in the centrosome. It is an integral component of the pericentriolar material (PCM). The protein contains a series of coiled-coil domains and a highly conserved PCM targeting motif called the PACT domain near its C-terminus. The protein interacts with the microtubule nucleation component gamma-tubulin and is likely important to normal functioning of the centrosomes, cytoskeleton, and cell-cycle progression. Mutations in this gene cause Seckel syndrome-4 and microcephalic osteodysplastic primordial dwarfism type II. Two transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Cell biology; Tags and cell markers\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: PCNT\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC-p, IF\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Pericentrin\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: O95613; Mouse: P48725\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Pericentrin;Kendrin;Pericentrin-B\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 5116\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239280566451,"sku":"BT-AP12848-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239280599219,"sku":"BT-AP12848-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239280631987,"sku":"BT-AP12848-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_cc37515f-e91f-4662-b4b5-04b97520eea0.png?v=1769392459","url":"https:\/\/afsbio.com\/products\/pcnt-polyclonal-antibody-bt-ap12848","provider":"AFSBio Inc.","version":"1.0","type":"link"}