{"product_id":"pd1-monoclonal-antibody-bt-mca2876","title":"PD1 Monoclonal Antibody - BT-MCA2876","description":"\u003cp\u003ePD1 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA2876-50, BT-MCA2876-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB\/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Others\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: PD1\u003c\/p\u003e\n\n\u003cp\u003eApplications: FCM\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 8G5B12\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: PD1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human PD1 (AA: 192-288) expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Purified antibody in PBS with 0.05% sodium azide\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 31.6kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Q15116\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: PDCD1, PD-1, CD279, SLEB2, hPD-1, hPD-l, hSLE1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 5133\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238410051763,"sku":"BT-MCA2876-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238410084531,"sku":"BT-MCA2876-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_bdbf21bd-8322-4ab2-9a9f-850f672d49f4.png?v=1769380228","url":"https:\/\/afsbio.com\/products\/pd1-monoclonal-antibody-bt-mca2876","provider":"AFSBio Inc.","version":"1.0","type":"link"}