{"product_id":"pde11-rabbit-polyclonal-antibody-ra28603","title":"PDE11 Rabbit Polyclonal Antibody - RA28603","description":"PDE11 Rabbit Polyclonal Antibody\n\nSizes: 50μL, 100μL\n\nCatalogue Numbers: RA28603-50, RA28603-100\n\nCitations, Manuals and MSDS Available upon request.\n\nBackground: The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],\n\nCondition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\n\nStorage Instructions: -20°C\/1 year\n\nRecommended dilutions: WB 1：500-2000\n\nApplications: WB\n\nSpecies Cross-Reactivity: Human; Mouse; Rat\n\nGeneID (Human): 50940\n\nSWISS: Q9HCR9\n\nSource: Rabbit\n\nResearch Use Only","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45119579848883,"sku":"RA28603-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45119579881651,"sku":"RA28603-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_a67f6fda-6103-49ae-9cce-9280222bc636.png?v=1773354983","url":"https:\/\/afsbio.com\/products\/pde11-rabbit-polyclonal-antibody-ra28603","provider":"AFSBio Inc.","version":"1.0","type":"link"}