{"product_id":"pde11a-polyclonal-antibody-bs76645","title":"PDE11A Polyclonal Antibody-BS76645","description":"PDE11A Polyclonal Antibody\n\nCatalogue Numbers:BS76645-50, BS76645-100\n\nProduct: 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\n\nSwiss-Prot: Q9HCR9\n\nHost: Rabbit\n\nReactivity: Human, Mouse\n\nApplications: WB\n\nAll Applications: WB,1:500 - 1:2000\n\nBackground: The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been found for this gene.\n\nPurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\n\nStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\nSpecificity: Unmodification \n\nNote: For research use only, not for use in diagnostic procedure.\nAlternative Name: PDE11A;PPNAD2\n\nImmunogen: Recombinant fusion protein of human PDE11A(NP_058649.3).\n\nConjugate: Unconjugated\n\nModification: Unmodified ","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42895106146483,"sku":"BS76645-50","price":342.59,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42895106179251,"sku":"BS76645-100","price":589.65,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_09a25281-e04a-4c81-92a5-3f6e01d6ac2e.jpg?v=1702573582","url":"https:\/\/afsbio.com\/products\/pde11a-polyclonal-antibody-bs76645","provider":"AFSBio Inc.","version":"1.0","type":"link"}