{"product_id":"pde1a-polyclonal-antibody-ra34035","title":"PDE1A Polyclonal Antibody - RA34035","description":"\u003cp\u003ePDE1A Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA34035-50, RA34035-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: phosphodiesterase 1A (PDE1A) Homo sapiens Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and\/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca (2+) \/calmodulin (see CALM1; MIM 114180) -dependent PDEs (CaM-PDEs) that are activated by calmodulin in the presence of Ca (2+) (Michibata et al., 2001 [PubMed 11342109]; Fidock et al., 2002 [PubMed 11747989]) .[supplied by OMIM, Oct 2009],\u003c\/p\u003e\n\n\u003cp\u003eCondition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eStorage Instructions: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eRecommended dilutions: WB 1:500-2000 ELISA 1:5000-20000\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; ELISA\u003c\/p\u003e\n\n\u003cp\u003eSpecies Cross-Reactivity: Human; Mouse\u003c\/p\u003e\n\n\u003cp\u003eGeneID (Human): 5136\u003c\/p\u003e\n\n\u003cp\u003eProtein MW (KDa): 58\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P54750\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45120581566643,"sku":"RA34035-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45120581599411,"sku":"RA34035-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_241b8580-67c0-4608-a269-cc934c04446f.png?v=1773367735","url":"https:\/\/afsbio.com\/products\/pde1a-polyclonal-antibody-ra34035","provider":"AFSBio Inc.","version":"1.0","type":"link"}