{"product_id":"pde1b-polyclonal-antibody-e-ab-60606","title":"PDE1B Polyclonal Antibody - E-AB-60606","description":"\u003cp\u003ePDE1B Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-60606-60, E-AB-60606-120, E-AB-60606-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: PDE1B\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: PDE1B; HEL-S-79p; PDE1B1; PDES1B\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer,Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, IHC\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: Q01064\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human PDE1B\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000, IHC 1:50-1:200\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 59kDa\/61kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 59kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146091364531,"sku":"E-AB-60606-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146091397299,"sku":"E-AB-60606-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146091430067,"sku":"E-AB-60606-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_c43d2ba5-2715-4654-849c-62e891e9e9a7.png?v=1710290846","url":"https:\/\/afsbio.com\/products\/pde1b-polyclonal-antibody-e-ab-60606","provider":"AFSBio Inc.","version":"1.0","type":"link"}