{"product_id":"pde1c-polyclonal-antibody-e-ab-91038","title":"PDE1C Polyclonal Antibody - E-AB-91038","description":"\u003cp\u003ePDE1C Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-91038-60, E-AB-91038-120, E-AB-91038-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: PDE1C\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: PDE1C; Hcam3; cam-PDE 1C; hCam-3; cam-PDE1C\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q14123\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes an enzyme that belongs to the 3'5'-cyclic nucleotide phosphodiesterase family. Members of this family catalyze hydrolysis of the cyclic nucleotides, cyclic adenosine monophosphate and cyclic guanosine monophosphate, to the corresponding nucleoside 5'-monophosphates. The enzyme encoded by this gene regulates proliferation and migration of vascular smooth muscle cells, and neointimal hyperplasia. This enzyme also plays a role in pathological vascular remodeling by regulating the stability of growth factor receptors, such as PDGF-receptor-beta.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human PDE1C\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.01% thiomersal, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 72kDa\/80kDa\/86kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 81kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43148771197107,"sku":"E-AB-91038-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43148771229875,"sku":"E-AB-91038-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43148771262643,"sku":"E-AB-91038-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_665c5bee-ede5-491f-a3f1-59cca77265cf.png?v=1710329655","url":"https:\/\/afsbio.com\/products\/pde1c-polyclonal-antibody-e-ab-91038","provider":"AFSBio Inc.","version":"1.0","type":"link"}