{"product_id":"pde3a-phospho-ser312-rabbit-polyclonal-antibody-ra36848","title":"PDE3A (Phospho-Ser312) Rabbit Polyclonal Antibody - RA36848","description":"\u003cp\u003ePDE3A (Phospho-Ser312) Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA36848-50, RA36848-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: phosphodiesterase 3A (PDE3A) Homo sapiens This gene encodes a member of the cGMP-inhibited cyclic nucleotide phosphodiesterase (cGI-PDE) family. cGI-PDE enzymes hydrolyze both cAMP and cGMP, and play critical roles in many cellular processes by regulating the amplitude and duration of intracellular cyclic nucleotide signals. The encoded protein mediates platelet aggregation and also plays important roles in cardiovascular function by regulating vascular smooth muscle contraction and relaxation. Inhibitors of the encoded protein may be effective in treating congestive heart failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011],\u003c\/p\u003e\n\n\u003cp\u003eCondition: Liquid in PBS containing 50% glycerol, and 0.164% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eStorage Instructions: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eRecommended dilutions: WB 1:500-2000\u003c\/p\u003e\n\n\u003cp\u003eAlternative Names: cGMP-inhibited 3',5'-cyclic phosphodiesterase A (EC 3.1.4.17) (Cyclic GMP-inhibited phosphodiesterase A) (CGI-PDE A)\u003c\/p\u003e \n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eSpecies Cross-Reactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eGeneID (Human): 5139\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q14432\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45120380403891,"sku":"RA36848-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45120380436659,"sku":"RA36848-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_18b64284-34ca-4756-9997-ad35f2145781.png?v=1773364271","url":"https:\/\/afsbio.com\/products\/pde3a-phospho-ser312-rabbit-polyclonal-antibody-ra36848","provider":"AFSBio Inc.","version":"1.0","type":"link"}